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Alpha-Fetoprotein (AFP) - AFP

What does the Alpha-Fetoprotein (AFP) - AFP blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:

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Alpha-Fetoprotein (AFP) is a protein produced by the liver during fetal development. In adults, elevated AFP levels can indicate liver disease or certain types of cancer, particularly liver cancer and testicular cancer. This test is used to: 1. Screen for liver cancer in high-risk individuals 2. Monitor treatment effectiveness in patients with liver or testicular cancer 3. Assess the risk of certain birth defects during pregnancy AFP levels can also be elevated in non-cancerous liver conditions, such as cirrhosis or hepatitis. Regular monitoring of AFP levels, along with other diagnostic tests, helps in early detection and management of liver diseases and certain cancers.

Acceptable Range:   0 to 10
Ideal for Women:   <10
Ideal for Men:   <10
Ideal for Girls:   <10
Ideal for Boys:   <10
Test Method: blood

What do readings below 0 ng/mL for Alpha-Fetoprotein (AFP) - AFP mean?

A low AFP level (below 0 ng/mL) is generally not a cause for concern in adults. In fact, AFP levels are expected to be very low or undetectable in healthy adults. However, during pregnancy, abnormally low AFP levels might indicate:

  1. Incorrect estimation of gestational age
  2. Possible chromosomal abnormalities (e.g., Down syndrome)
  3. Potential miscarriage

It’s important to note that a single low AFP result should not be considered diagnostic. Further testing and consultation with a healthcare provider are necessary for proper interpretation.

What do readings above 10 ng/mL for Alpha-Fetoprotein (AFP) - AFP mean?

Elevated AFP levels (above 10 ng/mL) can indicate several conditions:

  1. Liver cancer (hepatocellular carcinoma)
  2. Testicular cancer or ovarian germ cell tumors
  3. Metastatic cancers affecting the liver
  4. Non-cancerous liver conditions (cirrhosis, hepatitis, liver damage)
  5. During pregnancy: neural tube defects or other fetal abnormalities

However, elevated AFP alone is not diagnostic. False positives can occur, and other factors like pregnancy or benign liver conditions can cause elevated levels. Additional tests, such as imaging studies or biopsies, are often needed for a definitive diagnosis. Regular monitoring and consultation with a healthcare provider are crucial for proper interpretation and management.

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