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Mean Corpuscular Volume - MCV

What does the Mean Corpuscular Volume - MCV blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:

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MCV measures the average size of red blood cells (RBCs). It's crucial for diagnosing different types of anemia and other blood disorders. A normal MCV indicates that RBCs are of standard size, while abnormal values can suggest various conditions: - Low MCV (microcytosis): May indicate iron deficiency anemia, thalassemia, or chronic disease. - High MCV (macrocytosis): Can suggest vitamin B12 or folate deficiency, liver disease, or certain medications. MCV is calculated by dividing the hematocrit by the RBC count. It's part of the RBC indices, which help characterize the type and cause of anemia. MCV is often interpreted alongside other CBC parameters for a comprehensive blood analysis.

Acceptable Range:   80 to 100
Ideal for Women:   80-96
Ideal for Men:   80-96
Ideal for Girls:   80-96
Ideal for Boys:   80-96
Test Method: Blood test

What do readings below 80 fL for Mean Corpuscular Volume - MCV mean?

A low MCV (< 80 fL) indicates microcytosis, where RBCs are smaller than normal. This can be caused by:

  1. Iron deficiency anemia: Most common cause, due to inadequate iron intake or absorption.
  2. Thalassemia: Genetic disorder affecting hemoglobin production.
  3. Chronic disease: Conditions like rheumatoid arthritis or cancer can affect RBC size.
  4. Lead poisoning: Rare but possible cause of microcytosis.

Further tests, such as iron studies or hemoglobin electrophoresis, may be needed to determine the underlying cause.

What do readings above 100 fL for Mean Corpuscular Volume - MCV mean?

A high MCV (> 100 fL) indicates macrocytosis, where RBCs are larger than normal. This can be caused by:

  1. Vitamin B12 deficiency: Often due to pernicious anemia or dietary deficiency.
  2. Folate deficiency: Can result from poor diet or malabsorption.
  3. Liver disease: Alcoholic liver disease is a common cause.
  4. Hypothyroidism: Can affect RBC production and size.
  5. Certain medications: Such as anticonvulsants or chemotherapy drugs.

Additional tests, like vitamin B12 and folate levels, may be necessary to identify the specific cause.

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