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Ceruloplasmin - CER

What does the Ceruloplasmin - CER blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:

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Ceruloplasmin is a protein produced by the liver that carries copper in the blood. This test measures the amount of ceruloplasmin in the blood and is primarily used to help diagnose Wilson's disease, a rare genetic disorder that causes copper to accumulate in the liver, brain, and other organs. It can also be used to evaluate copper metabolism disorders, assess liver function, and monitor certain inflammatory conditions. Ceruloplasmin levels may increase during pregnancy, infection, or inflammation, and decrease in conditions that affect copper metabolism or liver function.

Acceptable Range:   20 to 60
Ideal for Women:   20-60
Ideal for Men:   20-60
Ideal for Girls:   20-60
Ideal for Boys:   20-60
Test Method: blood

What do readings below 20 mg/dL for Ceruloplasmin - CER mean?

A low ceruloplasmin level may indicate:

  • Wilson’s disease
  • Severe liver disease
  • Malnutrition
  • Copper deficiency
  • Menkes disease (a rare genetic disorder of copper metabolism)
  • Protein-losing enteropathy

Low levels require further investigation, including copper tests and genetic testing, to determine the underlying cause and appropriate treatment.

What do readings above 60 mg/dL for Ceruloplasmin - CER mean?

An elevated ceruloplasmin level may indicate:

  • Acute or chronic inflammation
  • Infection
  • Rheumatoid arthritis
  • Pregnancy
  • Oral contraceptive use
  • Certain cancers (e.g., Hodgkin’s lymphoma)
  • Hyperthyroidism

High levels are less specific and may require additional tests to determine the underlying cause. They are often associated with inflammatory conditions or hormonal changes.

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