What does the Lyme Disease Antibodies - LD Ab blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:
The Lyme Disease Antibodies test detects antibodies produced by the immune system in response to *Borrelia burgdorferi*, the bacteria causing Lyme disease. This test is crucial for diagnosing Lyme disease, especially when clinical symptoms are ambiguous. It's typically performed in two steps: a sensitive enzyme immunoassay (EIA) or immunofluorescence assay (IFA), followed by a more specific Western blot test if the first test is positive. The test helps identify both current and past infections, as antibodies can persist for years after successful treatment. Early detection and treatment are vital to prevent complications such as arthritis, neurological problems, and heart issues.
A negative result in the Lyme Disease Antibodies test generally indicates that the person has not been infected with Borrelia burgdorferi. However, it’s important to note that antibodies may not be detectable in the early stages of infection (first few weeks). If Lyme disease is still suspected despite a negative result, the test may need to be repeated in a few weeks. False negatives can occur, especially if antibiotics were taken early in the infection.
A positive result in the Lyme Disease Antibodies test suggests current or past infection with Borrelia burgdorferi. However, a positive result alone doesn’t necessarily indicate active disease. It should be interpreted in conjunction with clinical symptoms and patient history. False positives can occur due to cross-reactivity with other conditions like autoimmune diseases or other tick-borne illnesses. In endemic areas, a positive result may reflect past exposure rather than current infection. Follow-up testing and clinical evaluation are typically necessary to confirm active Lyme disease.