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Total Iron Binding Capacity (TIBC) - TIBC

What does the Total Iron Binding Capacity (TIBC) - TIBC blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:

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TIBC measures the blood's capacity to bind transferrin with iron. It indirectly assesses transferrin levels, reflecting the body's iron stores. This test is crucial for diagnosing iron deficiency anemia, iron overload disorders, and monitoring iron metabolism. TIBC is often used in conjunction with serum iron and ferritin tests to provide a comprehensive picture of iron status. Elevated TIBC typically indicates iron deficiency, while decreased levels may suggest anemia of chronic disease or iron overload conditions like hemochromatosis. TIBC helps clinicians differentiate between various types of anemia and guides treatment decisions for iron-related disorders.

Acceptable Range:   250 to 450
Ideal for Women:   250-450
Ideal for Men:   250-450
Ideal for Girls:   250-450
Ideal for Boys:   250-450
Test Method: blood

What do readings below 250 µg/dL for Total Iron Binding Capacity (TIBC) - TIBC mean?

A low TIBC reading (below 250 µg/dL) may indicate:

  1. Iron overload conditions (e.g., hemochromatosis)
  2. Chronic liver disease
  3. Malnutrition
  4. Anemia of chronic disease
  5. Nephrotic syndrome

Low TIBC suggests that the body has excess iron or reduced ability to bind iron. This condition requires further investigation to determine the underlying cause and appropriate treatment.

What do readings above 450 µg/dL for Total Iron Binding Capacity (TIBC) - TIBC mean?

A high TIBC reading (above 450 µg/dL) typically suggests:

  1. Iron deficiency anemia
  2. Late-stage pregnancy
  3. Oral contraceptive use
  4. Chronic blood loss
  5. Polycythemia vera (in some cases)

Elevated TIBC indicates that the body is trying to compensate for low iron levels by increasing iron-binding proteins. This often occurs in iron deficiency anemia, where the body needs more iron but cannot obtain it. Further tests and clinical evaluation are necessary to confirm the diagnosis and determine appropriate treatment.

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