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Vitamin B12 (B12) - B12

What does the Vitamin B12 (B12) - B12 blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:

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Vitamin B12, also known as cobalamin, is essential for proper red blood cell formation, neurological function, and DNA synthesis. This test measures the amount of vitamin B12 in the blood to detect deficiencies or excesses. B12 is crucial for maintaining healthy nerve cells and producing genetic material. It works closely with folate in making red blood cells and helps iron function properly in the body. The body doesn't produce B12, so it must be obtained through diet or supplements. Common sources include meat, fish, eggs, and dairy products. Vegetarians and vegans may be at higher risk of deficiency.

Acceptable Range:   200 to 900
Ideal for Women:   350-600
Ideal for Men:   350-600
Ideal for Girls:   350-600
Ideal for Boys:   350-600
Test Method: blood

What do readings below 200 pg/mL for Vitamin B12 (B12) - B12 mean?

A low vitamin B12 level may indicate:

  1. Inadequate dietary intake (common in vegetarians and vegans)
  2. Malabsorption disorders (e.g., celiac disease, Crohn’s disease)
  3. Pernicious anemia (autoimmune condition affecting B12 absorption)
  4. Gastric surgery or disorders
  5. Certain medications interfering with absorption

Symptoms of deficiency can include fatigue, weakness, constipation, loss of appetite, weight loss, and neurological changes such as numbness and tingling in the hands and feet. Severe deficiency can lead to anemia, balance problems, depression, and memory issues.

What do readings above 900 pg/mL for Vitamin B12 (B12) - B12 mean?

High vitamin B12 levels are less common but may indicate:

  1. Excessive supplementation
  2. Liver disease
  3. Certain blood disorders (e.g., chronic myelogenous leukemia, polycythemia vera)
  4. Kidney disease

While high B12 levels are generally not considered harmful, they may mask underlying health conditions. In some cases, elevated B12 can be associated with increased cancer risk, though this relationship is not fully understood. It’s important to note that the body excretes excess B12 in urine, so toxicity from dietary sources is rare. However, unusually high levels should be investigated to rule out underlying health issues.

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