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Renin - REN

What does the Renin - REN blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:

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Renin is an enzyme produced by the kidneys that plays a crucial role in regulating blood pressure and fluid balance in the body. It is part of the renin-angiotensin-aldosterone system (RAAS), which helps control blood pressure, sodium levels, and fluid volume. The renin test measures the activity of this enzyme in the blood. It is often used in conjunction with other tests to diagnose conditions such as hypertension, kidney disorders, or adrenal gland problems. Renin levels can be affected by various factors, including posture, salt intake, and certain medications.

Acceptable Range:   0.2 to 3.3
Ideal for Women:   0.2 - 3.3
Ideal for Men:   0.2 - 3.3
Ideal for Girls:   0.2 - 3.3
Ideal for Boys:   0.2 - 3.3
Test Method: Blood test

What do readings below 0.2 ng/mL/hr for Renin - REN mean?

A low renin level may indicate:

  • Primary aldosteronism (overproduction of aldosterone by the adrenal glands)
  • Cushing’s syndrome
  • Liddle syndrome (a rare genetic disorder affecting kidney function)
  • Excessive sodium intake
  • Some forms of congenital adrenal hyperplasia

Low renin levels may suggest that the body is retaining too much sodium, which can lead to hypertension and other cardiovascular issues. Further testing may be needed to determine the underlying cause.

What do readings above 3.3 ng/mL/hr for Renin - REN mean?

A high renin level may indicate:

  • Renal artery stenosis (narrowing of the arteries that supply blood to the kidneys)
  • Dehydration or salt depletion
  • Certain types of kidney disease
  • Malignant hypertension
  • Addison’s disease (adrenal insufficiency)
  • Cirrhosis of the liver

Elevated renin levels can be associated with conditions that reduce blood flow to the kidneys or cause excessive sodium loss. This may lead to hypertension and other complications. Additional tests are usually required to determine the specific cause of high renin levels.

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