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Lipase - LIP

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The Lipase (LIP) test measures the amount of lipase enzyme in the blood. Lipase is primarily produced by the pancreas and plays a crucial role in digesting fats. This test is often used to diagnose or monitor conditions affecting the pancreas, such as pancreatitis (inflammation of the pancreas), pancreatic cancer, or cystic fibrosis. Elevated lipase levels can indicate pancreatic inflammation or damage, while decreased levels may suggest pancreatic insufficiency. The test is particularly useful in diagnosing acute pancreatitis, as lipase levels typically rise within 4-8 hours of pancreatic injury and remain elevated for 7-14 days.

Acceptable Range:   7 to 60
Ideal for Women:   7-60
Ideal for Men:   7-60
Ideal for Girls:   7-60
Ideal for Boys:   7-60
Test Method: blood

What do readings below 7 U/L for Lipase - LIP mean?

A low lipase level (below 7 U/L) may indicate:

  1. Pancreatic insufficiency: The pancreas is not producing enough enzymes.
  2. Cystic fibrosis: A genetic disorder affecting the pancreas and other organs.
  3. Chronic pancreatitis: Long-term inflammation of the pancreas.
  4. Certain medications: Some drugs can decrease lipase production.

Low lipase levels may lead to difficulties in digesting fats, potentially causing malnutrition, weight loss, and steatorrhea (fatty stools). Further tests may be needed to determine the underlying cause and appropriate treatment.

What do readings above 60 U/L for Lipase - LIP mean?

A high lipase level (above 60 U/L) may indicate:

  1. Acute pancreatitis: Sudden inflammation of the pancreas.
  2. Pancreatic cancer: Malignant growth in the pancreas.
  3. Pancreatic duct obstruction: Blockage in the pancreatic ducts.
  4. Peptic ulcer disease: Ulcers in the stomach or small intestine.
  5. Kidney disease: Impaired renal function can lead to elevated lipase levels.

Elevated lipase levels, especially when 3-10 times the upper limit, strongly suggest acute pancreatitis. However, other conditions can also cause increased lipase, so additional tests and clinical evaluation are usually necessary for a definitive diagnosis.

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