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Alanine Aminotransferase - ALT

What does the Alanine Aminotransferase - ALT blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:

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Alanine Aminotransferase (ALT) is an enzyme primarily found in liver cells. It's a crucial component of the Comprehensive Metabolic Panel, serving as a key indicator of liver health. When liver cells are damaged or die, ALT is released into the bloodstream, causing elevated levels in blood tests. This test is particularly sensitive to liver injury and can detect liver problems before other signs or symptoms appear. ALT levels can be affected by various factors, including liver diseases (such as hepatitis or cirrhosis), alcohol consumption, certain medications, and obesity. Regular monitoring of ALT levels is essential for assessing liver function, detecting liver damage early, and monitoring the progression of liver diseases or the effectiveness of treatments.

Acceptable Range:   7 to 55
Ideal for Women:   7-35
Ideal for Men:   10-40
Ideal for Girls:   7-35
Ideal for Boys:   10-40
Test Method: blood

What do readings below 7 U/L for Alanine Aminotransferase - ALT mean?

A low ALT level is generally not a cause for concern and is rarely considered clinically significant. In some cases, it may indicate:

  1. Vitamin B6 deficiency
  2. Chronic kidney disease
  3. Reduced liver function due to aging

However, these conditions are typically diagnosed through other means, and a low ALT alone is not diagnostic. If other liver function tests are normal, a low ALT is usually not investigated further. Always consult with a healthcare provider for proper interpretation of test results.

What do readings above 55 U/L for Alanine Aminotransferase - ALT mean?

Elevated ALT levels often indicate liver damage or disease. Possible causes include:

  1. Viral hepatitis (A, B, or C)
  2. Alcoholic liver disease
  3. Nonalcoholic fatty liver disease
  4. Drug-induced liver injury
  5. Liver cirrhosis
  6. Autoimmune hepatitis
  7. Hemochromatosis

The degree of elevation can provide clues about the underlying cause. Mild elevations may be due to obesity or medication effects, while significant elevations often indicate acute liver injury. Further testing and medical evaluation are typically necessary to determine the exact cause and appropriate treatment.

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