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Aspartate Aminotransferase - AST

What does the Aspartate Aminotransferase - AST blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:

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AST is an enzyme found primarily in the liver and heart. This test measures the amount of AST in the blood, which can indicate liver or muscle damage. Elevated levels may suggest liver disease, hepatitis, cirrhosis, or other conditions affecting the liver. It's also useful in monitoring liver function during treatment of liver disorders or when taking medications that can affect the liver. AST levels can rise due to heart attacks, muscle injuries, or intense exercise. The test is often performed alongside ALT (Alanine Aminotransferase) to provide a more comprehensive assessment of liver health.

Acceptable Range:   10 to 40
Ideal for Women:   10-35
Ideal for Men:   10-40
Ideal for Girls:   10-35
Ideal for Boys:   10-40
Test Method: blood

What do readings below 10 U/L for Aspartate Aminotransferase - AST mean?

Low AST levels are generally not a cause for concern. In rare cases, extremely low AST might indicate:

  1. Vitamin B6 (pyridoxine) deficiency
  2. Chronic kidney disease
  3. Pregnancy

However, these conditions typically present with other symptoms and abnormalities in other tests. A low AST alone is usually not indicative of a specific health issue and may simply reflect individual variation.

What do readings above 40 U/L for Aspartate Aminotransferase - AST mean?

Elevated AST levels can indicate liver damage or disease. Possible causes include:

  1. Viral hepatitis (A, B, or C)
  2. Alcoholic liver disease
  3. Nonalcoholic fatty liver disease
  4. Cirrhosis
  5. Liver cancer
  6. Medications toxic to the liver
  7. Heart attack or muscle injury
  8. Mononucleosis

The extent of elevation and results of other tests help determine the underlying cause. Persistent high AST levels warrant further investigation to identify and address the root cause.

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